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Low DHT doesn’t affect the development of the testicles (they can still produce sperm) and internal sexual organs and structures. A genetic mutation (change) that affects the production of the enzyme can cause low or no levels of DHT. It happens when their ovaries create excess androgens, including testosterone, which leads to increased DHT levels. Polycystic ovarian syndrome (PCOS) is a hormonal imbalance that affects females. DHT has different roles in different life stages for males — mainly during fetal development and puberty.
High levels of DHT can shrink your hair follicles and shorten the hair growth cycle, resulting in hair loss. Androgenic alopecia is commonly known as male pattern hair loss. People who have prostate cancer usually have an increase in DHT levels. This local DHT production stimulates normal prostate activity but also commonly leads to prostate growth. Effects mainly include prostate enlargement and male pattern hair loss in adulthood.
People with mild androgen insensitivity are born with male-typical sex characteristics, but they are often infertile and tend to experience breast enlargement at puberty. People with partial androgen insensitivity can have genitalia that look typical for females, genitalia that have both male and female characteristics, or genitalia that look typical for males. Androgen insensitivity syndrome is a condition that affects sexual development before birth and during puberty. No, but they’re both types of genetic conditions that affect sexual development. This causes a person who is genetically male to not have male genitals or other sexual traits that are typical for males.
Interestingly, newborns with CAIS have the same size of male newborns, suggesting that postnatal factors are involved in the final height in these individuals (16). Menstrual cycles do not appear since normal production of anti-mullerian hormone (AMH) by the testis impeded uterus, cervix and proximal vagina to development. The presence of inguinal hernia in a female child is rare and could indicate a CAIS diagnosis (13).
This means male sex development does not happen as normal. Children with AIS have XY chromosomes, but the genetic alteration they inherit prevents their body responding to testosterone (the sex hormone). Androgen insensitivity syndrome (AIS) is caused by a genetic alteration that means the body cannot respond to testosterone either completely or partially.
Testosterone is the sex hormone produced by the testicles. As such, affected individuals do not menstruate and are unable to conceive a child (infertile). It’s important to talk with your child about their AIS around the time of puberty. Sometimes, they wait until puberty to choose one. But some health experts think certain treatments, such as removal of the testicles, should happen before puberty. This gives your child’s body time to go through developmental changes. But CAIS (complete AIS) or MAIS might not be evident until the age of 11 or 12, when puberty begins.

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